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Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 28, 2014; 20(4): 923-942
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.923
Table 2 Prognostic value of CD133
MarkerPrognostic valueRef.
CD133Worse outcome and higher risk of metastasis[32]
Independent prognostic marker for overall survival[33]
Association with CSC resistance to 5FU-based chemotherapy in CRC[34]
Association with resistance to conventional radiotherapy in CRC[35]
Prediction of distant recurrences after chemoradiotherapy in colon cancer patients[35]
High tumorigenicity of CD133+ CRC cells compared to CD133- cells due to their interaction with CAFs by paracrine signaling axis of CXCR4-SDF1[36]
Risk factor for poor overall survival in stage II and III in colon cancer patients[37]
Relationship with K-Ras and B-Raf mutations in CRC patients[38]