Biopsy-driven diagnosis in infants with cholestatic jaundice in Iran

Table 4 Mean laboratory findings from each diagnosed cause of infantile cholestasis

Cause	Total bilirubin in mg/dL	Direct bilirubin in mg/dL	ALP in IU/L	AST in IU/L	ALT in IU/L	GGT in IU/L	PT in sec	PTT in sec	Hgbin g/dL	Platelet×103/μL
BA	14.4	8.0	1230	313	310	597a	14.0	38	9.7	390
INH	10.5	6.0	1343	287	113	-	16.0	44	10.0	406
Paucity of bile ducts	11.5	6.5	1475	223	250	310	18.0	37	11.0	410
PFIC	28.0	13.0	1455	65	57	44	12.0	39	9.5	700
Choledochal cyst	11.5	5.2	1667	212	170	-	13.0	33	8.5	300
Metabolic disease	13.8	6.7	843	205	114	66	13.0	34	9.5	355
Cirrhosis	11.6	5.3	1710	226	45	-	16.0	76a	12.0	200
Portal fibrosis	8.0	5.1	453	380	120	-	13.5	39	10.0	187

^aP < 0.05. ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; Hgb: Hemoglobin; PT: Prothrombin time; PTT: Partial thromboplastin time.