Managing osteoporosis in ulcerative colitis: Something new?

Table 3 Effect on nonvertebral/hip fracture rates (from randomized controlled trials)

	Nonvertebral		Hip
	Osteoporosis (without prevalent vertebral fractures)	Established osteoporosis (with prevalent vertebral fractures)	Osteoporosis (without prevalent vertebral fractures)	Established osteoporosis (with prevalent vertebral fractures)
Raloxifene	NA	●	NA	NA
Alendronate	■	■	NA	■
Risedronate	NA	■	NA	■
Ibandronate	NA	●	NA	NA
Zoledronate	■	NA	■	NA
Teriparatide	NA	■	NA	NA
Strontium Ranelate	●	■	●	▲
Denosumab	■	NA	■	NA

■ Denotes a preplanned analysis in the entire study population; ▲ Denotes a preplanned analysis on a subset of the study population; ● Denotes a post hoc analysis. NA: No evidence available. Adapted from: Body et al[12].