Clinical features, outcomes and treatment-related pneumonitis in elderly patients with esophageal carcinoma

Table 2 Univariate analysis of prognostic factors

	n	Survival rate (elderly)			P	n	Survival rate (non-elderly)			P
		1 yr	3 yr	5 yr			1 yr	3 yr	5 yr
Gender					0.837					0.800
Male	93	66.5%	10.8%	2.2%		87	71.3%	12.7%	0.5%
Female	36	77.8%	8.3%	-		20	77.5%	5.3%	1.6%
Tumor type					0.878					0.039
Squamous	102	67.5%	11.2%	1.5%		103	74.8%	11.7%	0.3%
Non-squamous	27	75.9%	5.6%	0%		4	25.0%	-	-
Tumor location					0.360					0.212
Upper thoracic	29	72.4%	8.6%	4.3%		38	71.1%	17.5%	4.8%
Mid-thoracic	61	71.9%	12.1%	0%		46	67.4%	4.3%	-
Lower thoracic	39	62.8%	10.3%	-		23	87.0%	10.8%	-
Lymphatic metastasis					0.053					0.063
N0	74	77.0%	9.5%	1.0%		37	81.1%	18.5%	2.0%
N1	55	59.6%	9.3%	0.5%		70	68.6%	6.6%	0%
Distant metastasis					0.000					0.000
M0	123	71.4%	10.9%	1.7%		93	81.7%	12.9%	2.0%
M1	6	20.8%	-	-		14	14.3%	-	-
TNM stage					0.000					0.000
I	68	80.9%	11.8%	0.8%		33	84.8%	23.9%	5.1%
II	37	67.1%	11.2%	0.5%		46	91.3%	0.79%	-
III	18	44.0%	2.5%	0%		14	42.9%	-	-
IV	6	25.0%	-	-		14	14.3%	-	-
TRP					0.000					0.026
Yes	33	59.1%	0%	-		21	57.1%	-	-
No	96	72.8%	13.5%	2.2%		86	76.7%	13.1%	1.8%
TRP grade					0.000					0.047
II	20	81.0%	0%	-		14	64.0%	-	-
III	13	22.1%	-	-		7	42.9%	-	-
IV	0	-	-	-		0	-	-	-
Radiation dose					0.620					0.969
≤ 60 Gy	58	72.4%	10.3%	0%		54	70.4%	13.9%	0.5%
> 60 Gy	71	67.4%	10.4%	2.3%		53	75.5%	7.0%	1.5%

TNM: Tumor, node, metastasis; TRP: Treatment-related pneumonitis.