Otilonium bromide in irritable bowel syndrome: A dose-ranging randomized double-blind placebo-controlled trial

Figure 3 Effect of otilonium bromide (20, 40, 80 mg) and placebo on the frequency of evacuations (A) and the presence of mucus in stool, incomplete evacuation or difficulty of evacuation (B). Data are presented as % change from baseline values. Asterix denotes level of statistical significance (^bP < 0.01) for placebo vs 80 mg OB at 4 wk.