Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer

Table 2 Univariate analysis of clinicopathological factors for overall survival of colorectal cancer patients

Variable	Cases	HR	95%CI	P value
Gender			0.582-1.874	0.885
Male	56	1
Female	55	1.004
Age (yr)			0.820-2.738	0.189
≤ 60	51	1
< 60	60	1.498
Tumor size			0.921-3.124	0.090
≤ 5 cm	50	1
> 5 cm	61	1.696
Differentiation			0.852-3.098	0.140
Well, moderate	84	1
Poor	27	1.625
Venous invasion			2.058-7.781	< 0.001b
Negative	95	1
Positive	16	4.002
Depth of invasion			1.494-15.589	0.009b
T1, T2	23	1
T3, T4	88	4.826
Location			0.673-1.945	0.619
Rectum	58	1
Colon	53	1.144
Lymph node metastasis			3.194-13.937	< 0.001b
Absent	56	1
Present	55	6.672
miR-193a-5p expression			1.340-4.653	0.004b
High	55	1
Low	56	2.497

^bP < 0.01 vs control group. T: Tumor.