Connexin 32 and 43 promoter methylation in Helicobacter pylori-associated gastric tumorigenesis

Figure 4 Screenshots of bisulfite polymerase chain reaction sequencing of the Cx32 and Cx43 promoter CpG islands. The upper two show the 10^thCx32 CpG site (155bp), with the C/(C+T) ratio of 60% in NM and 80% at GC stage. The lower two shows the 10^th and 11^thCx43 CpG sites (190bp, 198bp). Dark arrow indicates the peak of the sulfonated methyl-CpG site still as C; red arrow indicates the sulfonated non-methylated CpG site changed as T.