Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy

Table 1 Patient characteristics in patients with low or high platelet count after major liver resection n (%)

Clinical characteristics	Low platelet group(n = 146)	High platelet group(n = 419)	P value
Male	131 (89.7)	353 (84.2)	0.104
Age > 65 yr	23 (15.8)	51 (12.2)	0.269
Preoperative platelet < 100 × 109/L	79 (54.1)	28 (6.7)	< 0.001
ASA grade			0.058
I-II	117 (80.1)	369 (88.1)
III	24 (16.4)	42 (10.0)
IV	5 (3.4)	8 (1.9)
BMI (kg/m2), mean (SD)	22.93 (2.80)	22.90 (2.83)	0.941
Esophageal varices	22 (15.1)	47 (11.2)	0.221
Hypertension	30 (20.5)	66 (15.8)	0.184
Cardiovascular disease	3 (2.1)	12 (2.9)	0.822
Pulmonary disease	3 (2.1)	9 (2.1)	1.000
Diabetes mellitus	22 (15.1)	26 (76.2)	0.001
HBsAg	124 (84.9)	330 (78.8)	0.106
HBeAg	22 (15.1)	58 (13.8)	0.714
HBV DNA > 2000 U/mL	51 (34.9)	135 (32.2)	0.548
AST (U/L) > ULN	68 (46.6)	194 (46.3)	0.954
ALT (U/L) > ULN	49 (33.6)	133 (31.7)	0.685
Total bilirubin (μmol/L), median (IQR)	14.5 (10.3-18.6)	12.9 (9.9-18.0)	0.145
Albumin (g/L), median (IQR)	40.9 (43.1-37.6)	40.5 (37.6-43.2)	0.538
Hemoglobin (g/L), median (IQR)	141 (129-150)	140 (127-152)	0.913

BMI: Body mass index; HBsAg: Hepatitis B surface antigen; HBeAg: Hepatitis B e antigen; SD: Standard deviation; ULN: Upper limit of normal; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ASA: American Society of Anesthesiologists category; IQR: Interquartile range.