Advances in the management of peritoneal mesothelioma

Table 3 Morbidity, peri-operative mortality, and length of stay associated cytoreduction with hyperthermic intraperitoneal chemotherapy

Ref.	Year	Sample No.	Complication rate	Peri-operative mortality	Re-operation	Abdominal	Cardiac/pulmonary	Sepsis	Wound Infection	Other infection	Renal	Vascular	Hematologic	Other	LOS
Park et al[33]	1999	18	24%		1	1	1	1	2	1				1
Feldman et al[48]	2003	49	25%	0	2	4	5	2	3	1	1			2
Costamagna et al[61]	2003	24	26%	11
Brigand et al[6]	2006	15	40%	0	0					0	0			0	16.3
Elias et al[60]	2007	26	54%	4	4	1	1			4	1	3	2	2	281
Gomez et al[113]	2007	7	71%												41.51
Hesdorffer et al[55]	2008	27	30%	0		2	1			1		1		3
Passot et al[114]	2008	22	47%	0
Chua et al[115]	2009	20	65%	1		2	5	2			1		1	3	16.51
Yano et al[62]	2009	17	41%	5.8			2			2		1		3
Kluger et al[54]	2010	47	34%	2	1	3	9	2	2	9	2	1		1	161
Cao et al[46]	2012	294	33%	2		50	38				26		15		231
Alexander et al[47]	2013	211	30%	2.3	20	20	25		9			6	8	11	11
Wong et al[52]	2013	29	65%	4	1	4	1		6		2		10	4	9
Deraco et al[37]	2003	19	25%	0		3				1	1			3	321
Deraco et al[39]	2003	28	14%	0
Deraco et al[38]	2003	61	23%	0		7
Deraco et al[40]	2006	49	15%G3			9	2	4		5	4		3	5	241
Deraco et al[50]	2013	116	41%G3	2.6											25
Baratti et al[36]	2007	12	8%G3	0	1	1
Baratti et al[116]	2008	5	20%G3	0	1	1
Baratti et al[35]	2010	83	28%G3	2.4
Baratti et al[117]	2010	12	8%G3	0											18
Baratti et al[53]	2012	60	28%G3	0	7	8	4	3	1		7	2	5	1
Baratti et al[34]	2013	108	39%	1.9		14	10	6			10		7
Yan et al[45]	2006	100	36%G3	5		6	8	7		11		5	8	10	221
Yan [44]	2007	70	41%G3	3	4	3	4	3		2		4	5	3	231
Yan et al[42]	2009	401	46%G3	2		74	57				39		25		221

¹Mean values. Cells with the superscript G3 represent grade 3 or above complications. Abdominal complications include perforation, abscess formation, dehiscence, and fistula. "Other" complications include neurological and musculoskeletal complaints, emesis, and dehydration. Numerical values represent cases or patient number unless otherwise stated.