Lower serum folate is associated with development and invasiveness of gastric cancer

Table 4 Univariate analysis of mortality predictors in gastric cancer patients

	Hazard ratio	95%CI	P value1
Age
> 60 vs ≤ 60	1.27	0.97-1.67	NS
Gender
Male vs female	1.29	0.98-1.69	NS
Stage
Advanced vs early	7.78	3.96-15.26	< 0.001
Depth of invasion
Serosal vs non-serosal invasion	3.96	2.67-5.89	< 0.001
Lymph node metastasis
Yes vs no	2.47	1.78-3.43	< 0.001
Lymphatic invasion
Yes vs no	2.17	1.53-3.07	< 0.001
Venous invasion
Yes vs no	2.45	1.73-3.46	< 0.001
Liver metastasis
Yes vs no	6.01	4.04-8.93	< 0.001
Folate
≤ 1.90 vs > 1.90 ng/mL	1.84	1.04-3.27	0.036

¹All P values ≥ 0.05 were considered to be statistically non-significant (NS).