Lower serum folate is associated with development and invasiveness of gastric cancer

Table 1 Demographic data and folate concentrations of gastric cancer patients and controls

	Case (n = 155)	Control (n = 149)	P value1
Age (yr)	62.02 ± 1.14	57.21 ± 0.86	< 0.01
Gender n (%)
Male	88 (56.8)	90 (60.4)	NS
Female	67 (43.2)	59 (39.6)
H. pylori infection n (%)
No	83 (53.5)	78 (52.3)	NS
Yes	72 (46.5)	71 (47.7)
Folate (ng/mL)	3.71 ± 0.30	8.00 ± 0.54	< 0.01
Male	3.12 ± 0.34	7.34 ± 0.74	< 0.01
Female	4.49 ± 0.54	9.01 ± 0.76	< 0.01
Age ≥ 60	3.70 ± 0.42	9.87 ± 1.17	< 0.01
Age < 60	3.72 ± 0.43	6.78 ± 0.43	< 0.01

¹All P values ≥ 0.05 were considered to be statistically non-significant (NS).