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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 28, 2014; 20(32): 11033-11053
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11033
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11033
Table 7 Combination algorithms of non-invasive methods for liver fibrosis proposed in chronic hepatitis C
| Algorithm’s name | Type | Non-invasive methods adopted | AUC for≥F2 | AUC for F4 | Saved liver biopsies for > F2 (%) | Saved liver biopsies for F4 (%) | Number of studies (patients) |
| SAFE biopsy[133,165] | Stepwise | APRI, Fibrotest® | 0.89-0.94 | 0.87-0.92 | 43.8-54.0 | 74.8-93.4 | 6 (4118) |
| Bordeaux algorithm[167,168] | Synchronous | Fibrotest, Fibroscan® | 0.88-0.91 | 0.93-0.95 | 71.9-77.0 | 78.8-79.0 | 3 (875) |
| Leroy algorithm[124] | Synchronous | APRI, Fibrotest® | 0.94 | NA | 19.0-29.2 | NA | 3 (1381) |
| Fibropaca algorithm[134] | Synchronous | APRI, Fibrotest, Forns’ index | 0.88 | 0.85 | 51.7 | 76.2-81.3 | 2 (1248) |
| Angers algorithms[171] | Synchronous | Fibrotest, Fibrometer® | 0.892 | 0.917 | 79.8 | 89.7 | 1 (390) |
| Bourliere’s algorithm[166] | Stepwise | APRI, Hepascore | 91%-96% (accuracy) | 33-45 | 1 (467) | ||
| Fibrometer® + Fibroscan[172] | Synchronous | Fibrometer, Fibroscan | 86.7% | 100 | 1 (1785) | ||
- Citation: Sebastiani G, Gkouvatsos K, Pantopoulos K. Chronic hepatitis C and liver fibrosis. World J Gastroenterol 2014; 20(32): 11033-11053
- URL: https://www.wjgnet.com/1007-9327/full/v20/i32/11033.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i32.11033