Serum beta 2-microglobulin as a biomarker in inflammatory bowel disease

Table 2 Overall accuracy and receiver operating characteristic analyses of beta 2 microglobulin and other inflammation markers to differentiate active from inactive ulcerative colitis

	AUC	Sensitivity (%)	Specificity (%)	NPV (%)	PPV (%)
B2-M (cut off: 2.02)	0.757	79.3	78.6	88.5	64.7
CRP (cut off: 0.55)	0.731	67.9	75.0	86.4	50.0
WBC (× 103)	0.656	72.4	58.3	80.8	46.7
(cut off: 6.50)
ESR (cut off: 14.5)	0.677	69.0	58.3	80.0	43.8

AUC: Area under the curve; B2-M: Beta 2 microglobulin; CRP: C reactive protein; WBC: White blood count; ESR: Erythrocyte sedimentation rate; NPV: Negative predictive value; PPV: Positive predictive value.