Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Aug 21, 2014; 20(31): 10682-10690
Published online Aug 21, 2014. doi: 10.3748/wjg.v20.i31.10682
Table 2 Mechanisms that cause a reduction in food intake in patients with cirrhosis
Reduced nutrient intakeDecreased appetite and anorexiaUnpalatable diet (sodium and water restriction for peripheral oedema and ascites, protein restriction for hepatic encephalopathy)
Dysgeusia due to micronutrient deficiencies (zinc or magnesium)
Anorexic effect caused by increased levels of proinflammatory cytokines (TNFα, IL-1β, IL-6) and leptin
Nausea and early satietyTense ascites
Gastroparesis
Small bowel dysmotility
Bacterial overgrowth
Frequent compulsory starvationHospitalisation
Invasive diagnostic procedures requiring fasting
Gastrointestinal bleeding and endoscopic therapy