Familial colorectal cancer: A review

Table 3 Colonoscopy-based screening controlled studies: Risk of advanced adenomas

Design	Age (yr)	No relatives/no controls	AA in relatives/AA in controls	OR	95%CI	Ref.
Prospective, case-control	40-74	185/370	10.8%/4.9%	2.5	1.1-5.4	[32]
Prospective, case-control	40-50	228/220	5.3%/2.3%	2.56	0.87-7.47	[33]
Prospective, cross-sectional	45-75	1252/765	11.3%/6.3%	2.41	1.69-3.43	[39]
Prospective, cross-sectional	40-70	374/374	7.5%/2.9%	3.07	1.50-6.30	[42]

AA: Advanced adenomas; OR: Odds ratio.