©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jul 28, 2014; 20(28): 9253-9260
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9253
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9253
Table 1 Current stage of development of direct antiviral agents
| Inhibitors of the NS3/4A serine protease | |
| First-generation | |
| Boceprevir | Approved |
| Telaprevir | Approved |
| Faldaprevir | Active clinical development |
| Sovaprevir | Active clinical development |
| Asunaprevir | Active clinical development |
| Simeprevir | Active clinical development |
| Danoprevir | Active clinical development |
| Vaniprevir | Active clinical development |
| Second-generation | |
| MK-5172 | Active clinical development |
| NS5A inhibitors | |
| Daclatasvir | Advanced clinical development |
| GS-5885 | Active clinical development |
| ABT-267 | Active clinical development |
| PPI-461 | Active clinical development |
| MK-8762 | Active clinical development |
| NS5B polymerase inhibitors | |
| Nucleos(t)ide inhibitors | |
| Sofosbuvir | Advanced clinical development |
| Mericitabine | Active clinical development |
| ALS-2200 | Active clinical development |
| Non-nucleos(t)ide inhibitors | |
| Setrobuvir | Active clinical development |
| ABT-333 | Active clinical development |
| GSK625433 | Active clinical development |
- Citation: Dall’Agata M, Gramenzi A, Biselli M, Bernardi M. Hepatitis C virus reinfection after liver transplantation: Is there a role for direct antiviral agents? World J Gastroenterol 2014; 20(28): 9253-9260
- URL: https://www.wjgnet.com/1007-9327/full/v20/i28/9253.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i28.9253