Risk factors and surgical outcomes for spontaneous rupture of BCLC stages A and B hepatocellular carcinoma: A case-control study

Table 3 Predictors of survival on multivariate analysis using a Cox regression model in patients with spontaneous rupture of hepatocellular carcinoma

Variable	Overall survival			Disease-free survival
	HR	95%CI	P value	HR	95%CI	P value
Age	1.01	0.99-1.03	0.348	1.02	0.99-1.05	0.097
Liver cirrhosis (yes vs no)	1.05	0.55-2.03	0.878	1.29	0.54-3.09	0.566
BCLC stage (stage A vs stage B)	1.35	0.60-3.06	0.470	1.13	0.41-3.07	0.817
Tumor size	0.96	0.88-1.06	0.456	0.92	0.81-1.05	0.235
Tumor location	1.02	0.59-1.76	0.936	1.24	0.64-2.42	0.524
Satellite nodule(s) (yes vs no)	0.77	0.46-1.27	0.299	0.76	0.39-1.47	0.413
Blood loss	1.00	1.00-1.00	0.085	1.00	1.00-1.00	0.940
Blood transfusion (yes vs no)	1.00	0.51-1.98	0.994	1.12	0.49-2.59	0.788
Radical resection (yes vs no)	0.32	0.08-0.61	0.015	0.12	0.01-0.73	0.002

HCC: Hepatocellular carcinoma; HR: Hazard ratio; CI: Confidence interval; BCLC: Barcelona clinic liver cancer.