Molecular biomarkers for the detection of metastatic colorectal cancer cells

doi:10.3748/wjg.v20.i27.8928

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2014; 20(27): 8928-8938
Published online Jul 21, 2014. doi: 10.3748/wjg.v20.i27.8928

Table 2 Comparison of biomarkers for detection of metastatic colorectal cancer cells

Marker	Stable	Amplifiable	Widely reported	FDA approval	False negative	False positive	Ref.
DNA methylation	●	●			●		[16]
mRNA		●	●			●	[7]
Micro RNA	●	●					[81]
CellSearch (EpCAM)	●			●	●		[39]
Genetic mutation	●	●			●		[15]

EpCAM: Epithelial cell adhesion molecule; FDA: Food and Drug Administration.

Citation: Kamiyama H, Noda H, Konishi F, Rikiyama T. Molecular biomarkers for the detection of metastatic colorectal cancer cells. World J Gastroenterol 2014; 20(27): 8928-8938
URL: https://www.wjgnet.com/1007-9327/full/v20/i27/8928.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i27.8928