High fat diet feeding results in gender specific steatohepatitis and inflammasome activation

Figure 5 Long-term high fat diet results in hepatic inflammation in male mice. A-C: Liver tumor necrosis factor-α (TNFα) protein levels (A) were evaluated in the short-term feeding levels of TNFα in the liver were analyzed at the mRNA (B) and protein (C) level after a long-term feeding; D-F: Monocyte chemoattractant protein 1 (MCP-1) protein levels (D) were evaluated in the short-term feeding. Levels of MCP-1 in the liver were analyzed at the mRNA (E) and protein (F) level after a long-term feeding. ^bP < 0.01 vs chow fed controls, n = 10/group.