Observational Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jul 14, 2014; 20(26): 8667-8673
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8667
Table 3 Inflammatory cytokines in liver transplant recipients, non-alcoholic steatohepatitis and controls
Variable (median - 25th-75th percentile)NASH (n = 22)LT (n = 44)1Controls (n = 20)P
TNFα (pg/mL)13.4 (8.85-22.2)12.1 (8.58-26.6)10.1 (5.0 -13.6)0.121
IFNγ (pg/mL)411.9 (192.3-1361.7)626.1 (286.9-1572.3)67.9 (42.2-100.6)< 0.001
IL-8 (pg/mL)57.8 (43.8-70.2)36.5 (31.2-44.9)40.7 (36.5-53.3)< 0.001
IL-10 (pg/mL)32.3 (22.5-49.8)32.3 (25.8-62.5)62.5 (34.4-85.3)0.019
1Comparisons: IFNγ (NASH = LT-P = 0.3; NASH and LT > controls - P < 0.001); IL-8 (NASH > LT - P < 0.001; NASH > controls - P = 0.04; LT = controls - P = 0.11); IL-10 (NASH = LT - P = 0.84; NASH < controls - P = 0.02; LT < controls - P = 0.04).