Effect of complication grade on survival following curative gastrectomy for carcinoma

Table 2 Survival analysis of all patients with gastric cancer

Characteristic	S	5-yr OS	Univariate analysis		Multivariate analysis
			χ2	P value	HR (95%CI)	P value
Age (yr)			15.816	< 0.001	1.378 (1.147-1.654)	0.001
≤ 65	402	42.8
> 65	349	28.7
Gender			1.842	0.175
Male	516	34.3
Female	235	40.9
Other diseases			2.457	0.117
No	567	37.2
Yes	184	33.7
BMI			1.675	0.196
Normal	561	37.6
Abnormal	190	32.6
Tumor size			57.692	< 0.001	1.296 (1.049-1.600)	0.016
< 5 cm	291	52.9
≥ 5 cm	460	25.9
Intraoperative blood loss (mL)			22.678	< 0.001	1.259 (1.038-1.526)	0.019
< 200	338	45.3
≥ 200	413	29.1
Tumor location			29.940	< 0.001	1.078 (0.99-01.173)	0.086
Upper 1/3	189	31.2
Middle 1/3	78	37.2
Lower 1/3	336	44.6
2/3 or more	148	23.0
Histology			0.895	0.344
Differentiated	251	37.8
Undifferentiated	500	35.6
Extranodal metastasis			42.214	< 0.001	1.190 (0.956-1.482)	0.120
Positive	139	18.7
Negative	612	40.5
Serosal invasion			44.226	< 0.001	1.185 (0.878-1.600)	0.266
No	146	61.0
Yes	605	30.4
Lymph node metastasis			159.593	< 0.001	1.342 (1.211-1.487)	< 0.001
pN0	210	66.2
pN1	116	38.8
pN2	175	28.0
pN3	250	15.6
TNM stage			182.016	< 0.001	1.525 (1.238-1.879)	< 0.001
I	58	79.3
II	174	59.2
III	464	25.9
IV	55	5.6
Chemotherapy			0.420	0.517
Yes	421	35.2
No	330	37.6
Type of gastrectomy			13.241	< 0.001	1.073 (0.881-1.307)	0.485
Subtotal	522	40.2
Total	229	27.5
Complication grade			131.080	< 0.001	1.456 (1.343-1.579)	< 0.001
None	446	43.0
GradeI	105	42.5
GradeII	106	25.5
GradeIII	94	9.6