Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population

Table 4 Genotype frequency of rs962917 and rs1545620 SNPs in Crohn’s disease phenotypes, n (%)

CD (n = 207)	rs962917			rs1545620
	CC (21)	CT (79)	TT (107)	AA (26)	AC (63)	CC (118)
Age, CD
A1 (< 16 yr)	1 (4.7)	4 (5.1)	5 (4.7)	1 (3.9)	3 (4.7)	6 (5.1)
A2 (17-40 yr)	14 (66.7)	51 (64.6)	68 (63.6)	16 (61.5)	41 (65.1)	76 (64.4)
A3 (> 40 yr)	6 (28.6)	24 (30.3)	34 (31.7)	9 (34.6)	19 (30.2)	36 (30.5)
Disease location, CD
L1	9 (42.8)	28 (35.4)	38 (35.5)	11 (42.3)	22 (34.9)	42 (35.6)
L2	6 (28.6)	15 (19.0)	21 (19.6)	7 (26.9)	12 (19.0)	24 (20.3)
L3	6 (28.6)1	36 (45.6)	48 (44.9)	8 (30.8)2	29 (46.0)	52 (44.1)
L4	2 (9.5)	7 (8.9)	9 (8.4)	2 (7.7)	6 (9.5)	10 (8.5)
Disease behavior, CD
B1	6 (28.6)	24 (30.4)	33 (30.8)	8 (30.8)	19 (30.2)	36 (30.5)
B2	9 (42.8)	32 (40.5)	44 (41.1)	11 (42.3)	26 (41.2)	48 (40.7)
B3	6 (28.6)	23 (29.1)	30 (28.1)	7 (26.9)	18 (28.6)	34 (28.8)
P	5 (23.8)	18 (22.9)	24 (22.4)	3 (11.5)3	16 (25.3)	28 (23.7)

Genotype frequencies in patients and controls were compared using the χ² test;

¹P = 0.014 CC vs CT TT;

²P = 0.022 AA vs AC CC;

³P = 0.029 AA vs AC CC. CD: Crohn’s disease.