Recurrent Clostridium difficile infections: The importance of the intestinal microbiota

doi:10.3748/wjg.v20.i23.7416

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2014; 20(23): 7416-7423
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7416

Table 4 Characteristics of some recent studies concerning fecal microbiota transplantation in recurrent Clostridium difficile infection treatment

Ref.	Study type	Patients (n)	FMT delivery modality	Success rate	Follow-up
Garborg et al[35], 2010	Retrospective study	40	Gastroscope	73% after 1 instillation	10 wk
Garborg et al[35], 2010	Retrospective study	40	Colonoscope	83% after 2 instillations	10 wk
Burke et al[36], 2013	Review	115	Naso-enteric tube	89.6%	2 mo to 5 yr
			Gastroscope
			Colonoscope
			Retention enema
Gough et al[32], 2011	Review	317	Naso-enteric tube	89% after 1 instillation	3 d to 5 yr
			Gastroscope	92% after ≥ 2 instillations
			Colonoscope
			Retention enema
Kassam et al[33], 2013	Meta-analysis	273	Naso-enteric tube	89%	2 wk to 8 yr
			Gastroscope
			Colonoscope
			Retention enema
Van Nood et al[38], 2013	Randomized controlled trial	43	Naso-duodenal tube	81.3% after 1 instillation	10 wk
Van Nood et al[38], 2013	Randomized controlled trial	43	Naso-duodenal tube	93.8% after 2 instillations	10 wk

FMT: Fecal microbiota transplantation.

Citation: Zanella Terrier MC, Simonet ML, Bichard P, Frossard JL. Recurrent Clostridium difficile infections: The importance of the intestinal microbiota. World J Gastroenterol 2014; 20(23): 7416-7423
URL: https://www.wjgnet.com/1007-9327/full/v20/i23/7416.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i23.7416