Reduced expression of circulating microRNA-218 in gastric cancer and correlation with tumor invasion and prognosis

Table 3 Cox regression analysis parameters for overall survival in gastric cancer (Backward: LR)

Variable	B	SE	Wald	df	P value	HR	95%CI
miR-218 expression (high vs low)	1.161	0.8556	4.284	1	0.035	3.162	1.062-9.401
T-status (T1-2vs T3-4)	1.713	0.4126	5.536	1	0.027	3.347	1.193-31.643
N-status (N0-1vs N2-3)	2.026	0.583	8.746	1	0.007	9.321	2.438-37.465
Metastasis (non-M vs M)	-1.463	0.522	7.698	1	0.005	0.231	0.091-0.653
Grade1	1.162	0.484	5.782	1	0.016	3.212	1.230-8.265
Grade2	2.312	0.664	12.136	1	0.000	10.061	2.753-36.857

¹Moderately differentiated vs well differentiated;

²Poorly differentiated vs well differentiated. B: Coefficient; df: Degree of freedom; M: Metastasis; non-M: Non-Metastasis; miR: microRNA.