Critical pathogenic steps to high risk Helicobacter pylori gastritis and gastric carcinogenesis

Figure 1 Neutrophilic proliferative zone foveolitis. A: Intense infiltration specifically focused on the proliferative zone of gastric pits (arrows). (HE, × 40); B: Neutrophils targeting the proliferative zone foveolar epithelium (arrows), while the surface is free of significant infiltration (long arrow) (HE, × 30); C: Infiltrate consisting of pure neutrophils in single cells or small aggregates (arrows). Neutrophils in lamina propria close to the foveolitis (arrowheads), suggesting an active movement into the epithelium (HE, × 150).