Value of 18F-FDG PET-CT in surveillance of postoperative colorectal cancer patients with various carcinoembryonic antigen concentrations

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2014; 20(21): 6608-6614
Published online Jun 7, 2014. doi: 10.3748/wjg.v20.i21.6608

Table 3 Diagnostic performance comparisons in case-based and lesion-based analyses

	PET/CT and CT in all patients		PET/CT in patients with different CEA levels
	PET/CT	CT	PET/CT (CEA ≤ 3.4 ng/mL)	PET/CT (CEA > 3.4 ng/mL)
Case-based analysis
Sensitivity (%)	95.2 (79/83)¹	80.7 (67/83)¹	83.3 (10/12)	97.2 (69/71)
Specificity (%)	82.6 (19/23)	73.9 (17/23)	85.7 (12/14)	77.8 (7/9)
Accuracy (%)	92.5 (98/106)²	79.3 (84/106)²	84.6 (22/26)	95 (76/80)
Lesion-based analysis
Sensitivity (%)	96.1 (146/152)³	83.1 (118/142)³	81.3 (13/16)⁵	97.8 (133/136)⁵
Specificity (%)	81.4 (35/43)	73.5 (25/34)	80 (16/20)	82.6 (19/23)
Accuracy (%)	92.8 (181/195)⁴	81.3 (143/176)⁴	80.6 (29/36)⁶	95.6 (152/159)⁶

¹χ² = 8.186, P = 0.004;

²χ² = 6.201, P = 0.013;

³χ² = 13.445, P = 0.000;

⁴χ² = 11.194, P = 0.001;

⁵χ² = 6.432, P = 0.011;

⁶χ² = 7.837, P = 0.005. PET: Positron emission tomography; CT: Computerized tomography; CRC: Colorectal cancer.

Citation: Zhang Y, Feng B, Zhang GL, Hu M, Fu Z, Zhao F, Zhang XL, Kong L, Yu JM. Value of ¹⁸F-FDG PET-CT in surveillance of postoperative colorectal cancer patients with various carcinoembryonic antigen concentrations. World J Gastroenterol 2014; 20(21): 6608-6614
URL: https://www.wjgnet.com/1007-9327/full/v20/i21/6608.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i21.6608

Zhang Y, Feng B, Zhang GL, Hu M, Fu Z, Zhao F, Zhang XL, Kong L, Yu JM. Value of ¹⁸F-FDG PET-CT in surveillance of postoperative colorectal cancer patients with various carcinoembryonic antigen concentrations. World J Gastroenterol 2014; 20(21): 6608-6614 [PMID: 24914384 DOI: 10.3748/wjg.v20.i21.6608]

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