MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: Current status and future prospects

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 20

Peer-Review Report of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. May 28, 2014; 20(20): 5973-5986
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.5973

Table 2 Examples of miRNAs involved in chronic hepatitis B infection or hepatitis B virus-related hepatocellular carcinoma

miRNA	Target gene	Process(es) affected
miR-1	HDAC4	HBV replication
miR-1	E2F5	Cell proliferation; cell cycle
miR-199a-3p, miR-210	HBV genome	HBV replication and antigen production
miR-501	HBXIP	HBV replication
miR-141	PPARA	HBV replication
miR-29a	PTEN	Cell migration
miR-101	DNMT3A	DNA methylation and gene silencing
let-7	STAT3	Cell proliferation
miR-148a	HPIP	Cell proliferation; migration; EMT

Their validated miRNA targets and subsequent effects on cells are listed accordingly. HBV: Hepatitis B virus; EMT: Epithelial-mesenchymal transition.

Citation: Tan YLJ, Chen WN. MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: Current status and future prospects. World J Gastroenterol 2014; 20(20): 5973-5986
URL: https://www.wjgnet.com/1007-9327/full/v20/i20/5973.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i20.5973

Tan YLJ, Chen WN. MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: Current status and future prospects. World J Gastroenterol 2014; 20(20): 5973-5986 [PMID: 24876720 DOI: 10.3748/wjg.v20.i20.5973]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.