Prognostic factors for hepatocellular carcinoma recurrence

Table 2 Risk factors predicting hepatocellular carcinoma recurrence after surgical treatments

Treatment	Recurrence	Risk factors	Ref.
Liver resection	Early	Tumor size ≥ 5 cm	[50,51]
		High histological grade (G4)	[58-61]
		Microvascular invasion	[53]
		Resection technique	[67-70]
		Genetic profile	[123]
	Late	Stage of liver disease	[46,51]
		Multinodularity	[51]
		Age	[65]
		Gender (male)	[65]
		AST > × 2 normal values	[65]
		Genetic profile	[124]
Orthotopic liver transplant		Milan criteria	[77]
		Vascular invasion	[78]
		Bilobar nodules	[81]
		Tumor grade	[83]
		Tumor size > 5 cm	[80]
		Total number of lesions	[82]

AST: Aspartate aminotransferase.