Long-term follow-up of ulcerative colitis patients treated on the basis of their cytomegalovirus antigen status

Table 3 Multivariate analysis of factors predictive of colectomy in ulcerative patients with positive cytomegalovirus antigen status

Risk factor	Risk ratio	95%CI		Pvalue
		Lower	Upper
Gender (male)	0.38	0.03	4.24	0.42
Age (> 45 yr)	1.22	0.15	12	0.85
Duration of disease (> 2 yr)	0.98	0.09	9.18	0.98
Severity (severe)	8.37	0.46	751	0.17
Extent of disease (total colitis)	2.43	0.15	118	0.55
Apheresis use	0.87	0.08	9.59	0.91
CNI use	0.54	0.01	10.2	0.69
Ganciclovir use	0.04	0.01	0.5	0.01
Dose reduction of corticosteroids	0.76	0.03	13.1	0.85
Number of CMV Ag1 (> 3)	3.77	0.53	42.3	0.19

¹This number means the maximum of CMV Ag detected during the period. CMV Ag: Cytomegalovirus antigenemia assay; CAI: Clinical activity index.