Point shear wave elastography method for assessing liver stiffness

Table 2 Performance of point shear wave elastography (n = 98) and transient elastography (n = 101) in patients with chronic hepatitis C

Parameter	Method	F≥2	F≥3	F= 4
Cut-off in kPa	PSWE	5.7	5.8	7.2
	TE	6.9	7.3	9.3
AUC	PSWE	0.80 (0.71-0.87)	0.88 (0.80-0.94)	0.95 (0.89-0.99)
	TE	0.82 (0.73-0.89)	0.95 (0.88-0.98)	0.92 (0.85-0.97)
Sensitivity %	PSWE	62.0 (47.2-75.3)	85.2 (66.3-95.8)	90.0 (55.5-99.7)
	TE	62.7 (48.1-75.9)	89.9 (70.8-97.6)	90.0 (55.5-99.7)
Specificity %	PSWE	91.7 (80.0-97.7)	84.5 (74.0-92.0)	88.6 (80.1-94.4)
	TE	83.7 (70.3-92.7)	80.8 (69.9-89.1)	87.8 (79.2-93.7)
PPV %	PSWE	88.6 (73.3-96.8)	67.6 (49.5-82.6)	47.4 (24.4-71.1)
	TE	80.0 (64.1-91.1)	63.2 (45.7-78.4)	45.0 (23.1-78.5)
NPV %	PSWE	69.8 (57.0-80.8)	93.7 (84.7-98.3)	98.7 (93.1-100)
	TE	68.3 (55.0-79.7)	95.2 (86.5-99.0)	98.7 (93.2-100)
+LR	PSWE	7.4 (2.8-19.5)	5.5 (3.1-9.7)	7.9 (4.3-14.7)
	TE	3.8 (2.0-7.5)	4.6 (2.8-7.6)	7.4 (4.1-13.3)
-LR	PSWE	0.4 (0.3-0.6)	0.2 (0.07-0.4)	0.1 (0.02-0.7)
	TE	0.4 (0.3-0.6)	0.1 (0.05-0.4)	0.1 (0.02-0.7)

In parentheses: 95%CI. PSWE: Point shear wave elastography; TE: Transient elastography; kPa: Kilopascals; AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.