Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats

doi:10.3748/wjg.v20.i16.4753

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4753-4760
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4753

Table 2 Effect of a Cichorium intybus L. extract on serum alanine aminotransferase and aminotransferase levels in rats

Treatment	AST (U/L)	ALT (U/L)
Control	60.84 ± 13.36	48.74 ± 8.98
CCl₄	711.14 ± 165.78^b	738.81 ± 231.66^b
6 g/kg CIE + CCl₄	194.86 ± 44.25^d	123.65 ± 29.93^d
18 g/kg CIE + CCl₄	154.29 ± 41.97^d	120.18 ± 28.26^d
54 g/kg CIE + CCl₄	149.04 ± 34.44^d	100.72 ± 27.19^d
FFBJRGP (780 mg/kg)	132.75 ± 34.78^d	71.57 ± 15.65^d

Values are expressed as the mean ± SD, n = 12. Compared with control group,

^bP < 0.01; Compared with CCl₄-exposed group,

^dP < 0.01. AST: Aminotransferase; ALT: Alanine aminotransferase; CIE: Cichorium intybus L. extract; FFBJRGP: Fu Fang Bie Jia Ruan Gan Pian.

Citation: Li GY, Gao HY, Huang J, Lu J, Gu JK, Wang JH. Hepatoprotective effect of Cichorium intybus L., a traditional Uighur medicine, against carbon tetrachloride-induced hepatic fibrosis in rats. World J Gastroenterol 2014; 20(16): 4753-4760
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4753.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4753