Hepcidin expression in colon during trinitrobenzene sulfonic acid-induced colitis in rats

Table 1 Macroscopic evaluation, myeloperoxidase activity, body weight and cytokine production in colon tissues

	Control	Colitis
Damage score	0 (0-1)	5 (4-9)a
Myeloperoxidase activity (U/g tissue)	2.2 ± 0.6	18.2 ± 4.8b
Initial body weight (g)	299 ± 8	303 ± 3
Final body weight (g)	405 ± 9	368 ± 4a
Microscopic score	2 (0-3)	11 (6-14)a
TNF-α (pg/mg protein)	1.8 ± 1.2	7.4 ± 2.1a
IL-6 (pg/mg protein)	8.2 ± 1.7	14.7 ± 0.7a
IL-10 (pg/mg protein)	23.5 ± 3.4	12.1 ± 1.7b

^aP < 0.05 and

^bP < 0.01 compared with the control group (n = 5-7). TNF-α:Tumor necrosis factor-alpha; IL: Interleukin.