MicroRNAs in colorectal cancer as markers and targets: Recent advances

Table 2 Colorectal cancer-associated microRNAs without identified target

MiR (family)	Role/potential	Ref.
1	TS	[76-78]
7	TS	[79,80]
10b	Marker, +, chemo	[83]
15a	TS	[84]
18a	ON	[87,88]
19 family	Marker, +, chemo	[18,53,89]
23a	ON	[94,95]
27b	TS	[96]
29 family	Marker, +	[55,87,97,98]
30a-5p	TS	[99]
32	ON	[100]
93	TS	[79,104,105]
96	Marker, +	[17]
101	TS	[14,107,108]
103/107	ON	[109]
106 family	ON	[14,42,46,47]
122	ON	[110]
124	TS	[111-113]
125 family	TS	[114]
126	Marker, +	[115]
127-3p	Marker, +	[40]
129	TS	[116]
130a/301a/454	ON	[117]
133 family	Marker, -	[78,118]
135 family	ON	[17,20,24,48,49]
137	TS	[112,119,120]
140	Marker, +	[38,123]
141	Circ, Marker, +	[124]
144	Marker, -	[125,126]
146a	SNP	[127,128]
149	Marker, -	[129]
150	Marker, -	[130]
181a	ON	[131]
182	Marker, +	[36,132]
185	Marker, +	[118]
186, 216b, 337-3p	TS	[133]
190b	Marker, +, chemo	[55]
192	Marker, -	[74]
193a-3p, 338-5p	Circ, Marker, +	[94]
194	Marker	[53,74]
19, 512, 801, 246	Marker, +	[123]
196a2	SNP	[134-138]
199a-5p	TS	[139]
206	Marker, +	[24]
211	ON	[140]
212	TS	[141]
218	TS	[142]
221*, 224	TS	[143]
222	TS	[144]
223	TS	[145]
297	TS	[146]
328	TS	[149]
330	TS	[150]
340	TS	[112]
345	TS	[153]
362-3p	TS	[154]
367	SNP	[156]
372	Marker, +	[21]
375, 422a	TS	[20]
378	Marker, -	[20,40]
409-3p	Cirl, Marker, +	[79]
424*	TS	[65]
429	ON	[158]
450 family, 99a*	Marker, -, chemo	[55]
451	TS	[159]
486-3p	Marker, +	[40]
493, 493*	TS	[160]
497	TS	[161]
502	TS	[163]
574-5p	ON	[165]
592	Marker, +	[38]
601	Marker, +	[166]
608	SNP	[167]
625-3p	Marker, +, chemo	[168]
627	TS	[169]
638	Marker, -	[53]
760	Marker, +	[133, 66]
1224-5p	Marker, -	[38]
1275	Marker, -	[53]

TS: Tumor suppressor; ON: Oncogene; Marker, +: Up-regulated marker; Marker, -: Down-regulated marker; Chemo: Chemosensitivity-associated; SNP: Single nucleotide polymorphism-associated.