Effect of precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis

Table 3 Interventions in various trials and pancreatitis definitions

Study	Precut timing	Timing for std cannulation	Type of pre cut	Use of GW	PD stent/PP	PEP criteria	Fellow involvement
Cennamo et al[13]	5 min of failed cannulation or 3 pancreatic duct cannulation	20 min post randomization	Papillotomy	Yes	No	Consensus	No
						Criteria
Tang et al[15]	12 min of failed cannulation	15 min post randomization	Papillotomy	No	No	Consensus	Yes
						Criteria
Khatibian et al[14]	Immediate precut	15 min post randomization	Fistulotomy	Yes	No	Consensus	No
						Criteria
de Weerth et al[12]	Immediate precut	20 min post randomization or 3 pancreatic cannulation	Papillotomy	Yes	N/A	Consensus	No
						Criteria
Zhou et al[11]	10 min of failed cannulation or 3 pancreatic duct cannulation	N/A	Papillotomy and fistulotomy	Yes	N/A	N/A	N/A
Manes et al[10]	10 min of failed cannulation or 5 pancreatic duct cannulation	10 min post randomization	Fistulotomy	Yes	No	Consensus	N/A
						Criteria
Swan et al[16]	5 min of failed cannulation or 2 pancreatic duct cannulation	10 min post randomization	Papillotomy	Yes	Yes1	Consensus	Yes
						Criteria

¹Subjects with inadvertent PD cannulation. GW: Guidewire; PP: Pharmacological prophylaxis for post ERCP pancreatitis; N/A: Data not available; PD: Pancreatic duct; PEP: Post ERCP pancreatitis; ERCP: Endoscopic retrograde cholangiopancreatography.