HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation

Table 3 Frequencies of human leukocyte antigen-C alleles in the acute cellular rejection group (n = 40) and the non-acute cellular rejection group (n = 102) in the total population (missing n = 1)

HLA-C allele	Acute rejection		No acute rejection		OR	95%CI	Uncorrected
	n (alleles)	(%)	n (alleles)	(%)			P value
*01	2	(2.5)	8	(3.9)	0.6	0.3-2.9	0.43
*02	2	(2.5)	11	(5.4)	0.5	0.1-1.8	0.24
*03	10	(12.5)	43	(21.1)	0.7	0.3-1.1	0.09
*04	8	(10.0)	24	(11.8)	1.1	0.4-2.2	0.89
*05	8	(10.0)	18	(8.8)	1.0	0.5-2.3	0.76
*06	6	(7.5)	16	(7.8)	1.2	0.5-2.8	0.82
*07	41	(51.2)	62	(30.4)	2.4	1.4-4.0	0.001
*08	2	(2.5)	4	(2.0)	1.1	0.3-4.7	0.54
*12	0	(0)	8	(4.2)	0.2	0.02-1.1	0.07
*14	0	(0)	1	(0.5)	0.9	0.08-9.4	0.72
*15	0	(0)	4	(2.0)	0.3	0.03-2.5	0.26
*16	0	(0)	3	(1.5)	0.4	0.04-3.2	0.31
*17	1	(1.2)	4	(2.0)	0.8	0.2-4.3	0.57

OR and corresponding 95%CI were calculated using Woolf’s formula with Haldane’s correction; uncorrected P value: calculated by the χ² test or the Fisher’s exact test where appropriate. HLA: Human leukocyte antigen.