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World J Gastroenterol. Apr 7, 2014; 20(13): 3401-3409
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3401
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3401
Figure 3 Ratcheting inchworm translocation.
Four consequent snapshots (A-D) within a single ligand-induced operation cycle are shown. Red bonds indicate connections between a motor domain and the DNA chain. After one cycle, the helicase is found in a similar open-shape conformation, but is propagated by one base along the DNA strand (compare A and D).
- Citation: Flechsig H. Computational biology approach to uncover hepatitis C virus helicase operation. World J Gastroenterol 2014; 20(13): 3401-3409
- URL: https://www.wjgnet.com/1007-9327/full/v20/i13/3401.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i13.3401