Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population

doi:10.3748/wjg.v20.i13.3655

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Apr 7, 2014; 20(13): 3655-3662
Published online Apr 7, 2014. doi: 10.3748/wjg.v20.i13.3655

Table 2 Distribution of genotype and allele frequencies of apolipoprotein C3 (-455, -482) and patatin-like phospholipase domain-containing protein 3 (rs738409) in nonalcoholic fatty liver disease patients and controls n (%)

	NAFLD	Controls	χ²	P value
-455 genotype
TT	102 (26.2)	104 (25.4)
TC	180 (46.2)	195 (47.7)
CC	108 (27.7)	110 (26.9)	0.186	0.911
Allele T	384 (49.2)	403 (49.3)
C	396 (50.8)	415 (51.2)	0.000	1.000
-482 genotype
CC	107 (27.4)	104 (25.4)
CT	176 (45.1)	203 (49.6)
TT	107 (27.4)	102 (51.2)	1.635	0.442
Allele C	390 (50.0)	411 (50.2)
T	390 (50.0)	407 (49.8)	0.010	0.960
rs738409 genotype
CC	48 (12.3)	183 (44.7)
CG	153 (39.2)	176 (43.0)
GG	189 (48.5)	50 (12.2)	160.98	0.000
Allele C	249 (31.9)	542 (66.3)
G	531 (68.1)	276 (33.7)	188.31	0.000

NAFLD: Nonalcoholic fatty liver disease.

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Citation: Niu TH, Jiang M, Xin YN, Jiang XJ, Lin ZH, Xuan SY. Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population. World J Gastroenterol 2014; 20(13): 3655-3662
URL: https://www.wjgnet.com/1007-9327/full/v20/i13/3655.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i13.3655

Niu TH, Jiang M, Xin YN, Jiang XJ, Lin ZH, Xuan SY. Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population. World J Gastroenterol 2014; 20(13): 3655-3662 [PMID: 24707151 DOI: 10.3748/wjg.v20.i13.3655]

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