Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population

Table 1 Demographic and clinical features of patients with nonalcoholic fatty liver disease and controls n (%)

	NAFLD patients(n = 390)	Controls(n = 409)	P value
BMI (kg/m2)	24.83 ± 2.82	22.18 ± 4.02	0.000a
Waist (cm)	84.18 ± 8.19	75.78 ± 9.13	0.000a
Hypertension	89 (22.8)	42 (10.3)	0.000c
T2DM	87 (22.3)	36 (8.8)	0.000c
ALT (U/L)	44.86 ± 40.16	34.32 ± 22.27	0.000a
AST (U/L)	33.40 ± 32.60	32.60 ± 36.42	0.762
GGT (U/L)	43.82 ± 42.17	34.00 ± 26.92	0.000a
FPG (mmol/L)	6.03 ± 1.77	5.18 ± 0.82	0.357
UA (mmol/L)	326.03 ± 105.24	332.88 ± 104.74	0.000a
TG (mmol/L)	2.91 ± 1.43	2.26 ± 1.55	0.000a
TC (mmol/L)	5.17 ± 1.00	4.77 ± 0.85	0.000a
HDL (mmol/L)	1.71 ± 0.99	2.38 ± 2.36	0.000a
LDL (mmol/L)	4.28 ± 3.44	3.17 ± 1.78	0.000a
FINS (μU/mL)	6.27 ± 1.34	5.51 ± 1.01	0.000a
HOMA-IR (U)	1.67 ± 0.62	1.27 ± 0.32	0.000a

Data are expressed as mean ± SD,

^aP < 0.05 vs controls, by unpaired Student’s t test;

^cP < 0.05 vs controls, by χ² test. Body mass index (BMI) was calculated as body weight (kg)/height (m²); ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyltransferase; FPG: Fasting blood glucose; UA: uric Acid; TC: Total cholesterol; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; FINS: Fasting blood insulin; NAFLD: Nonalcoholic fatty liver disease; TG: Triglyceride; HOMA-IR: Homeostatic model assessment of insulin resistance.