Glucose intolerance and diabetes mellitus in ulcerative colitis: Pathogenetic and therapeutic implications

Table 3 Management of active severe ulcerative colitis in diabetic patients treated with corticosteroids

Disease monitoring	Disease treatment
Regular monitoring of blood glucose level Regular monitoring of disease activity (e.g., Disease Activity Index) Plain abdominal X-ray	Rehydration with saline solution Correction of blood glucose levels Treatment of hypokaliemia Treatment of hypomagnesaemia
Dosage of: C-reactive protein Blood cell count Electrolytes Anion gap Osmolality Serum creatinine levels Ketones Urinalysis Blood gas analysis	Consider alternative treatments Iv cyclosporine A (4 mg/d) Infliximab (5 mg/kg or 10 mg/kg) Adalimumab (160 mg/80 mg/40 mg eow) Tacrolimus Leucocytapheresis Other therapies (vedolizumab, visilizumab, abatacept, tofacitinib)