Chronic hepatitis C virus infection and atherosclerosis: Clinical impact and mechanisms

Table 1 Main characteristics of the studies which evaluated the association between hepatitis C virus and atherosclerosis

Ref.	Type of study	Country	HCV+(n)	HCV-(n)
Studies showing association
Ishizaka et al[12], 2002	Population	Japan	104	4784
Ishizaka et al[13], 2003	Population	Japan	25	1967
Tomiyawa et al[20], 2003	Cohort	Japan	87	7427
Fukui et al[21], 2003	Cohort	Japan	31	179
Boddi et al[10], 2007	Cohort	Italy	31	120
Targher et al[15], 2007	Cohort	Italy	60	60
Butt et al[35], 2009	Observational cohort	United States	82083	89562
Mostafa et al[22], 2010	Cross-sectional	Egypt	329	795
Petta et al[23], 2012	Cohort	Italy	174	174
Adinolfi et al[9], 2013	Cohort	Italy	326	477
Studies showing no association
Bilora et al[28], 2008	Cohort	Italy	40	40
Caliskan et al[29], 2009	Cohort	Turkey	36	36
Tien et al[30], 2009	Cohort	United States	273	1502
Masiá et al[31], 2011	Cohort	Spain	63	138

HCV: Hepatitis C virus.