Chronic hepatitis C genotype 1 virus: Who should wait for treatment?

doi:10.3748/wjg.v20.i11.2867

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Mar 21, 2014; 20(11): 2867-2875
Published online Mar 21, 2014. doi: 10.3748/wjg.v20.i11.2867

Table 1 New drugs for treating chronic hepatitis C

Class	Drug	Phase of study
NS3/4A protease inhibitors	Telaprevir	Approved
	Boceprevir	Approved
	Simeprevir	III
	Faldaprevir	III
	Danoprevir	II
	Vaniprevir	II
	Narlaprevir	II
	Asunaprevir	II
	GS-9256	II
	GW-9451	II
	ABT-450/r	II
	ACH-1625	II
	ACH-2684	Ib
	MK-5172	II
Nucleoside/nucleotide analogue inhibitors of HCV-RNA dependent RNA polymerase	Sofosbuvir	III
	Mericitabine	II
	IDX184	II
	PSI-938	II
	INX-189	Ib
Non-nucleoside inhibitors of HCV-RNA dependent RNA polymerase	Tegobuvir	II
	Filibuvir	II
	Setrobuvir	II
	BI207127	II
	ABT-333	II
	VX-222	II
	TMC-647055	Ib
NS5A inhibitors of HCV-RNA dependent RNA polymerase	Daclatasvir	II
	PPI-461	Ib
	GS-5885	Ib
	GSK2336805	Ib
Cyclophilin inhibitors	Alisporivir	III
Cyclophilin inhibitors	SCY-465	II

Adapted from Pawlotsky et al[50]. HCV: Hepatitis C virus.

Citation: Tovo CV, Mattos AA, Almeida PRL. Chronic hepatitis C genotype 1 virus: Who should wait for treatment? World J Gastroenterol 2014; 20(11): 2867-2875
URL: https://www.wjgnet.com/1007-9327/full/v20/i11/2867.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i11.2867