TIPS improves liver transplantation-free survival in cirrhotic patients with refractory ascites: An updated meta-analysis

Table 2 Characteristics of the patients in the included studies

Patient characteristics	Lebrec et al[10]	Rössle et al[9]	Ginès et al[8]	Sanyal et al[11]	Salerno et al[12]	Narahara et al[13]
Number of randomized patients	12/13	29/31	35/35	52/57	33/33	30/30
Age, yr (mean)	50/52	58/61	59/56	56/52	58/60	58/61
Percentage of refractory ascites (total)	100/100 (100)	58/52 (55)	100/100 (100)	100/100 (100)	72/64 (75)	100/100 (100)
Percentage men (total)	77/66 (72)	72/68 (70)	69/74 (71)	63/70 (66)	72/76 (74)	77/70 (73)
Percentage alcohol-induced cirrhosis (total)	77/83 (80)	83/74 (78)	51/60 (56)	62/58 (60)	45/39 (42)	37/33 (35)
Percentage Child-Pugh class C (total)	31/33 (32)	38/22 (30)	37/43 (26)	NR	79/73 (76)	37/30 (33)
Mean Child-Pugh score	9.3/9.2	9.1/8.7	9.3/9.2	9.2/9.3	9.4/9.4	8.9/8.9
Percentage with HE (total)	15/17 (16)	46/39 (40)	37/40 (39)	NR	27/21 (24)	10/7 (8)
Percentage with previous GI bleeding (total)	NR	NR	34/23 (29)	23/25 (24)	18/21 (20)	NR
Serum bilirubin, mg/dL	2.04 ± 0.5/1.57 ± 0.2	1.8 ± 1.2/1.8 ± 1.0	2.0 ± 0.2/2.4 ± 0.3	1.9 ± 1.2/1.9 ± 1.4	1.7 ± 0.15/1.9 ± 0.24	1.3 ± 0.7/1.4 ± 0.7
Serum albumin, g/dL	3.0 ± 0.1/3.1 ± 0.2	3.5 ± 0.6/3.5 ± 0.4	2.8 ± 0.1/3.0 ± 0.1	2.9 ± 0.4/2.7 ± 0.4	2.9 ± 0.7/2.9 ± 0.8	2.7 ± 0.5/2.7 ± 0.6
Serum creatinine, mg/dL	0.9 ± 0.7/0.9 ± 0.6	1.3 ± 0.4/1.4 ± 0.9	1.4 ± 0.1/1.4 ± 0.1	1.1 ± 0.3/1.0 ± 0.3	1.12 ± 0.06/1.15 ± 0.09	1.03 ± 0.30/1.03 ± 0.35
Serum sodium, mmol/L	130 ± 2/130 ± 2	130 ± 6/131 ± 6	129 ± 1/130 ± 1	NR	133 ± 1/133 ± 1	134 ± 7/133 ± 5

All of the comparisons between groups were not statistically significant (P > 0.05) in any of the included studies. TIPS: Transjugular intrahepatic portosystemic shunt; HE: Hepatic encephalopathy; NR: Not reported; GI: Gastrointestinal.