Inflammatory bowel disease: Epidemiology, pathology and risk factors for hypercoagulability

doi:10.3748/wjg.v20.i1.53

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Jan 7, 2014 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2014; 20(1): 53-63
Published online Jan 7, 2014. doi: 10.3748/wjg.v20.i1.53

Table 2 Changes in coagulation and fibrinolytic systems in patients with in inflammatory bowel diseases

Coagulation factors	Fibrinolytic factors	Plasma coagulation inhibitors
Fibrynogen ↑	TAFI ↑	Antithrombin III ↓
Factor V ↑	PAI-1 ↑	TFPI ↓
Factor VII ↑	tPA ↓
Factor VIII ↑
Factor XI ↑
Prothrombin fragment 1 + 2 ↑
Thrombin-antithrombin complex ↑
TF ↑
FXIII ↓

tPA: Tissue plasminogen activator; TAFI: Thrombin-activatable fibrinolysis inhibitor; PAI-1: Plasminogen activator inhibitor 1; TFPI: Tissue factor pathway inhibitor.

Citation: Owczarek D, Cibor D, Głowacki MK, Rodacki T, Mach T. Inflammatory bowel disease: Epidemiology, pathology and risk factors for hypercoagulability. World J Gastroenterol 2014; 20(1): 53-63
URL: https://www.wjgnet.com/1007-9327/full/v20/i1/53.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i1.53