Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy

Table 1 Baseline characteristics of the included trials

Ref.	Disease	Sample size(LCVP/control)	LCVP technique	Transfusion trigger	Methodology score	Blinding (patient/surgeon/anesthesiologist)	Lost to follow-up
Liu et al[15] 2008	Hepatocellular carcinoma	23/23	Trendelenburg’s posture, nitroglycerine, furosemide, control of infusion speed	Hb < 80 g/L	3	Yes/no/no	0/46
Wang et al[16] 2006	Hepatocellular carcinoma	25/25	Trendelenburg’s posture, limiting the volume of infusion, nitroglycerine, furosemide	Hb < 80 g/L	4	Yes/no/no	0/52
Kato et al[17] 2008	Primary liver cancer, metastatic liver tumor	43/42	Clamping the infrahepatic inferior vena cava	Not reported	2	No/no/no	0/85
Liu et al[18] 2005	Not reported	30/30	Trendelenburg’s posture, isoflurane, fentanyl, limiting the volume of infusion, nitroglycerine	Blood loss exceeding 25% of the blood volume or Hb < 80 g/L	1	No/no/no	0/50
El-Kharboutly et al[19] 2004	Not reported	20/20	Nitroglycerine	Not reported	3	No/no/no	0/40

LCVP: Low central venous pressure.