Outcome of patients undergoing right lobe living donor liver transplantation with small-for-size grafts

Table 1 Clinical features of the recipients of liver grafts with an actuarial graft-to-recipient weight ratio < 0.8% and those with an actuarial graft-to-recipient weight ratio ≥ 0.8% n (%)

Variable	Total (n = 196)	Group A (n = 45)	Group B (n = 151)	P value
Recipient factors
Age (yr)	42.60 ± 9.05	42.60 ± 8.90	42.60 ± 9.13	0.673
Sex (male/female)	171/25	40/5	131/20	0.706
MELD score	16.42 ± 9.86	13.87 ± 9.09	17.19 ± 9.97	0.012a
Child-Pugh score	7.71 ± 2.12	7.27 ± 2.08	7.85 ± 2.20	0.118
aGRWR (%)	0.93 ± 0.18	0.71 ± 0.07	0.99 ± 0.15	< 0.001a
ABO-compatibility (yes/no)	161/35	36/9	125/26	0.669
Median follow-up (mo)	54.3	48.8	57.8	0.033a
2001-2005/2006-2010	22/174	2/43	20/131	0.101
ICU stay (h)	307.32 ± 305.86	277.07 ± 270.91	316.34 ± 315.81	0.189
Hospitalization time (d)	39.45 ± 25.21	38.84 ± 22.49	39.64 ± 26.03	0.970
Pre-transplant complications
Encephalopathy	21 (10.71)	4 (8.89)	17 (11.26)	0.860
GI bleeding	12 (6.12)	4 (8.89)	8 (5.30)	0.598
Peritonitis	8 (4.08)	0	8 (5.30)	0.251
Uncontrolled ascites	37 (18.88)	7 (15.56)	30 (19.87)	0.516
Renal insufficiency	7 (3.57)	0	7 (4.64)	0.311
Etiology				< 0.001a
Hepatic malignancy	89 (45.41)	28 (62.22)	61 (40.40)	0.010
Viral cirrhosis	66 (33.67)	7 (15.56)	59 (39.07)	0.003
Non-viral cirrhosis	11 (5.61)	4 (8.89)	7 (4.64)	0.472
Cholestasis	12 (6.12)	1 (2.22)	11 (7.28)	0.374
Acute liver failure	11 (5.61)	4 (8.89)	8 (5.30)	0.598
Other	6 (3.06)	1 (2.22)	5 (3.31)	0.710
Donor factors
Age (yr)	34.97 ± 10.20	34.29 ± 9.97	35.18 ± 10.30	0.727
Sex (male/female)	121/75	32/13	89/62	0.140
Body mass index	23.00 ± 2.55	22.96 ± 3.15	23.01 ± 2.36	0.654
Relationship (blood-related/non-blood-related)	20.41%/79.59%	13.33%/86.67%	22.52%/77.48%	0.180
	40/156	6/39	34/117
Operative factors
Operative time (min)	659.02 ± 132.78	662.24 ± 113.65	658.05 ± 138.30	0.472
Blood loss (mL)	2183.93 ± 2022.02	2014.44 ± 1765.92	2234.44 ± 2095.04	0.444
Ahepatic duration (min)	93.36 ± 41.82	87.47 ± 30.94	95.11 ± 44.49	0.412
MHV tributary drainage1	124 (63.27)	31 (68.89)	93 (61.69)	0.373
Concurrent splenectomy	11 (5.61)	3 (6.67)	8 (5.30)	0.726
Types of biliary reconstruction2	180/16	44/1	136/15	0.178
Complications after LDLT
Postoperative bleeding	8 (4.08)	1 (2.22)	7 (4.64)	0.773
Acute rejection	9 (4.59)	2 (4.44)	7 (4.64)	0.957
Vascular complications	7 (3.57)	1 (2.22)	6 (3.97)	0.922
Biliary complications	21 (10.71)	5 (11.11)	16 (10.60)	0.922
SFSS	16 (8.16)	7 (15.56)	9 (5.96)	0.080

¹MHV tributary drainage includes MHV tributary reconstruction and MHV trunk inclusion;

²Types of biliary reconstruction type includes duct-to-duct anastomosis and Roux-en-Y hepaticojejunostomy. GI: Gastrointestinal; MELD: Model for End-Stage Liver Disease; aGRWR: Actuarial graft-to-recipient weight ratio; MHV: Middle hepatic vein; LDLT: Living donor liver transplantation; SFSS: Small-for-size syndrome.

^aP < 0.05.