Epithelial-mesenchymal transition in colorectal cancer tissue of patients with Lynch syndrome

Table 5 The correlation of hMSH2, hMLH1, TGFβRII, E-cadherin, β-catenin, matrix metalloproteinase-7 and tissue inhibitor of metalloproteinase-2 expression in sporadic colorectal carcinoma

Sporadic CRC		hMSH2			hMLH1			TGFβRII			E-cadherin		Cytomembraneβ-catenin		Cytoplasmicβ-catenin		MMP-7
		(++)	(+)	(-)	(++)	(+)	(-)	(++)	(+)	(-)	(+)	(-)	(+)	(-)	(+)	(-)	(++)	(+)	(-)
hMLH1	(++)	0	14	0
	(+)	0	5	6
	(-)	0	0	5
TGFβRII	(++)	0	4	4	7	0	1
	(+)	0	10	4	7	5	2
	(-)	0	5	3	0	6	2
E-cadherin	(+)	0	12	6	12	4	2	6	9	3
	(-)	0	7	5	2	7	3	2	5	5
Cytomembrane β-catenin	(+)	0	13	2	9	5	1	6	8	1	12	3
	(-)	0	6	9	5	6	4	2	6	7	6	9
Cytoplasmic β-catenin	(+)	0	14	10	13	8	3	7	11	6	15	9	10	14
	(-)	0	5	1	1	3	2	1	3	2	3	3	5	1
MMP-7	(++)	0	6	4	6	2	2	7	3	0	8	2	5	5	7	3
	(+)	0	12	4	6	9	1	1	11	4	10	6	10	6	14	2
	(-)	0	1	3	2	0	2	0	0	4	0	4	0	4	3	1
TIMP-2	(++)	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	(+)	0	4	2	4	0	2	2	2	2	5	1	4	2	1	5	4	2	0
	(-)	0	15	9	10	11	3	6	12	6	13	11	11	13	23	1	6	14	4