Gastrointestinal sarcoidosis associated with pneumatosis cystoides intestinalis

Figure 2 Pathology of the resected tissue revealed portions of large bowel with submucosal and mucosal hemorrhage and submucosa with irregular spaces lined with histiocytes (CD68 positive and CD31 negative) consistent with pneumatosis cystoides intestinalis. A: Cecum specimen stained with hematoxylin and eosin demonstrates partially endotheliolized cystic spaces in the submucosa lined by eosinophilic cells characteristic of pneumatosis intestinalis; B: Immunohistochemical staining for CD 68 which is found in cytoplasmic granules of cells within the monocyte/macrophage lineage confirms presents of histiocytes lining cystic spaces.