Roux-en-Y versus Billroth I reconstruction after distal gastrectomy for gastric cancer: A meta-analysis

Table 4 Meta-analysis of outcomes of interest

Outcome of interest	Studies	Patients (n)	OR/WMD	95%CI	P value
RCT
Operation time	3	478	40.02	13.93, 66.11	0.003
Intraoperative blood loss	3	478	26.99	-9.35, 63.33	0.15
Hospital stay	3	478	2.96	-0.00, 5.93	0.05
Anastomotic leakage	3	478	0.56	0.12, 2.66	0.47
Anastomotic stricture	3	478	1.79	0.52, 6.13	0.36
Bile reflux	2	145	0.04	0.01, 0.14	< 0.00 001
Reflux esophagitis	3	458	0.49	0.20, 1.23	0.13
Remnant gastritis	2	363	0.43	0.28, 0.66	0.000
Delayed gastric emptying	2	363	2.31	0.12	44.41
OCS
Operation time	4	718	31.3	12.99, 49.60	0.001
Intraoperative blood loss	3	620	26.9	-46.54, 100.34	0.47
Hospital stay	2	522	1.40	-0.17, 2.97	0.08
Anastomotic leakage	5	813	1.26	0.40, 3.97	0.70
Anastomotic stricture	3	658	0.94	0.31, 2.89	0.91
Bile reflux	6	757	0.21	0.08, 0.54	0.001
Reflux esophagitis	5	719	0.48	0.26, 0.89	0.02
Remnant gastritis	6	784	0.18	0.11, 0.29	< 0.00 001
Dumping symptoms	4	347	0.59	0.32, 1.12	0.11
Delayed gastric emptying	4	701	0.95	0.24, 3.74	0.94

RCT: Randomized controlled trials; OCS: Non-randomized observational clinical studies; OR: Odds ratio; WMD: Weighted mean differences.