Risk factors for hepatic decompensation in patients with primary biliary cirrhosis

Table 1 Demographic and clinical laboratory characteristics of primary biliary cirrhosis patients at the time of entry (n = 262) n (%)

Age (yr), mean ± SD	51.5 ± 10.2
Gender (female/male), n	240/22
The symptomatic	170 (64.9)
Jaundice	78 (29.8)
Pruritus	69 (26.3)
Persistent fatigue	63 (24.0)
Pain in the right hypochondrium	40 (15.3)
UDCA responders	190 (72.5)
Early PBC	19 (7.3)
Extra-hepatic autoimmune diseases	96 (36.6)
Sjögren's syndrome	54 (20.6)
Autoimmune thyroid diseases	25 (9.5)
CREST/systemic sclerosis	8 (3.1)/3 (1.1)
Polymyositis/dermatomyositis	8 (3.1)/1 (0.4)
Systemic lupus erythematosus	4 (1.5)
Psoriasis	4 (1.5)
Rheumatoid arthritis	3 (1.1)
Takayasu’s arteritis	2 (0.8)
Histological stages	110 (42.0)
I-II	97 (88.2)
III-IV	13 (11.8)

UDCA: Ursodeoxycholic acid; PBC: Primary biliary cirrhosis; PBC: Primary biliary cirrhosis; CREST: Comprehensive overview covers symptoms, causes, treatment of this autoimmune disorder.