Controversial role of toll-like receptors in acute pancreatitis

Table 5 Toll-like receptors and acute pancreatitis

	Observed change	Tissue/cell	Ref.
TLR2	Increased mRNA expression	Pancreas	[35]
		Lungs	[40]
		Liver	[48,49]
	Increased protein levels	Pancreas	[35]
		Liver	[48]
	Decreased mRNA expression	Pulmonary macrophages	[43]
TLR4	Increased mRNA expression	Pancreas	[35,64,73,92]
		Lungs	[40,88]
		Liver	[48,94,96]
		Kidney	[96]
	Increased protein levels	Small intestine	[96]
		Pancreas	[35,92]
		Lungs	[88]
		Liver	[48,49]
		Intestine	[65]
		Blood monocytes	[106]
	Decreased mRNA expression	Pulmonary macrophages	[43]
TLR9	Increased mRNA expression	Pancreas	[117,118]
	Increased protein levels	Pancreas	[118]

TLR: Toll-like receptor.